Research
JDRF is the leading funder and advocate of type 1 science.
JDRF’s mission is to cure type 1 diabetes and its complications through the support of research. JDRF research is focused on improving the lives of people with diabetes today and in the future. JDRF-funded research encompasses type 1 diabetes at every life-stage: stopping or slowing its progression in people who are newly diagnosed; reversing it in those who have lived with the disease for years; avoiding or reversing complications; and preventing the disease in people at risk and in future generations.
JDRF Research Funding Facts
Download JDRF Research Funding Facts
- Since its founding 40 years ago, JDRF has funded $1.5 billion in type 1 diabetes research.
- We funded more than $107 million in diabetes research in 2010. That is more funding for type 1 diabetes than any other charity in the world.
- More than 80 percent of JDRF’s expenditures directly support research and research-related education.
- In 2010, JDRF funded research projects in 19 countries around the world, including over 40 clinical trials.
JDRF’s Research Goals
JDRF research is focused on improving the lives of people with diabetes today and in the future. Consistent with this goal, we focus on both short- and longer-term opportunities. Broadly, these are: science leading to better treatment, and science leading to a cure. To achieve these related goals, JDRF focuses its research on two main areas:
Cure Therapies:
- Beta Cell Therapies (replacing or regenerating the cells that produce insulin)
- Immune Therapies (reversing and preventing the immune system attack)
Treatment Therapies:
- Glucose Control (better control of blood sugar levels)
- Complications Therapies (stopping or reversing the progression of complications)
FY2010 JDRF Research Funding
Immune Therapies |
$32 million |
Beta Cell Therapies |
$35 million |
Glucose Control |
$23 million |
Complications Therapies |
$17 million |
Total |
$107 million |
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Stop the AttackThis area focuses on ways to stop the immune system attack on the body’s insulin-producing beta cells that causes type 1 diabetes. Within this area, JDRF is prioritizing antigen-specific therapies that would reverse the immune attack in type 1 diabetes without suppressing the entire immune system. |
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Tight ControlThis area seeks to identify ways to dramatically improve blood glucose control while avoiding dangerous highs and lows in people at all stages of type 1 diabetes. JDRF is prioritizing the development of a closed loop artificial pancreas, a device combining glucose monitors and insulin pumps, to enable people to achieve tight blood sugar control and reduce their risk of complications. JDRF is also prioritizing the development of novel insulins that are glucose-responsive, faster-acting, easier to use, and more effective. |
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Restore Beta CellsThis area aims to find ways to restore the body’s ability to make insulin through the:
JDRF is prioritizing regeneration because of its potential to restore beta cell function in the largest number of people living with type 1 diabetes. |
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Prevent, Stop, ReverseThis area seeks to identify ways to dramatically improve blood glucose control while avoiding dangerous highs and lows in people at all stages of type 1 diabetes. JDRF is prioritizing the development of a closed loop artificial pancreas, a device combining glucose monitors and insulin pumps, to enable people to achieve tight blood sugar control and reduce their risk of complications. JDRF is also prioritizing the development of novel insulins that are glucose-responsive, faster-acting, easier to use, and more effective. |
To help you better understand what is involved in participating in a clinical trial, and to simplify the process of finding trials that are of interest to you (or your child), JDRF has created an online customized clinical trials listing service - the JDRF Clinical Trials Connection.
JDRF offers a variety of local and national e-publications to help you stay connected to the information you care about.
As the leading charitable funder of diabetes research worldwide, the Juvenile Diabetes Research Foundation International offers a wide variety of grants and fellowships to qualified diabetes researchers.
Visit the JDRF International website to learn more.
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