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Research

JDRF is the worldwide leader for research to cure type 1 diabetes.

JDRF’s mission is to find a cure for diabetes and its complications through the support of research. JDRF is also committed to developing new and better treatments that improve the lives of people with type 1 diabetes in the near term and keep them healthy while we advance toward a cure.

 

JDRF Research Funding Facts

  • Since its founding in 1970 by parents of children with type 1 diabetes, JDRF has funded more than $1.4 billion in research. In FY2009 alone, JDRF funded nearly $101 million, more than $42 million of which represented new scientific projects.
  • In a typical year, 85 percent of JDRF’s expenditures directly support research and research-related education.
  • In FY2009, JDRF funded research projects in 22 countries, including more than 40 human clinical trials.

 

JDRF’s Research Goals

JDRF is committed to aggressively following the most promising paths to cure, better treat, and prevent type 1 diabetes. We are targeting our resources on science that seeks to:

  • Arrest the immune attack on the insulin-producing beta cells
  • Restore or replace beta cell function
  • Better control blood sugar levels
  • Protect people from – or reverse – complications

 

FY2009 JDRF Research Funding

Immune Therapies

$33 million

Beta Cell Therapies

$39.8 million

Glucose Control

$5.9 million

Complications Therapies

$22.1 million

Total

$100.8 million

 

Download JDRF Research Funding Facts

 

therapeutic areas

Immune Therapies

Stop the Attack

This area focuses on ways to stop the immune system attack on the body’s insulin-producing beta cells that causes type 1 diabetes. Within this area, JDRF is prioritizing antigen-specific therapies that would reverse the immune attack in type 1 diabetes without suppressing the entire immune system.

Glucose Control

Tight Control

This area seeks to identify ways to dramatically improve blood glucose control while avoiding dangerous highs and lows in people at all stages of type 1 diabetes. JDRF is prioritizing the development of a closed loop artificial pancreas, a device combining glucose monitors and insulin pumps, to enable people to achieve tight blood sugar control and reduce their risk of complications. JDRF is also prioritizing the development of novel insulins that are glucose-responsive, faster-acting, easier to use, and more effective.

Beta Cell Therapies

Restore Beta Cells

This area aims to find ways to restore the body’s ability to make insulin through the:

  • Regeneration of insulin-producing beta cells (i.e. triggering the body to re-grow beta cells) and
  • Replacement of the beta cells lost to diabetes

JDRF is prioritizing regeneration because of its potential to restore beta cell function in the largest number of people living with type 1 diabetes.

Complications Therapies

Prevent, Stop, Reverse

This area seeks to identify ways to dramatically improve blood glucose control while avoiding dangerous highs and lows in people at all stages of type 1 diabetes. JDRF is prioritizing the development of a closed loop artificial pancreas, a device combining glucose monitors and insulin pumps, to enable people to achieve tight blood sugar control and reduce their risk of complications. JDRF is also prioritizing the development of novel insulins that are glucose-responsive, faster-acting, easier to use, and more effective.

 

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clinical trials

To help you better understand what is involved in participating in a clinical trial, and to simplify the process of finding trials that are of interest to you (or your child), JDRF has created an online customized clinical trials listing service - the JDRF Clinical Trials Connection.

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Discovery to Development: Pathways for Advancing and Financing New Therapies

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for scientists

As the leading charitable funder of diabetes research worldwide, the Juvenile Diabetes Research Foundation International offers a wide variety of grants and fellowships to qualified diabetes researchers.

Visit the JDRF International website to learn more.

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