A key part of JDRF's research is aimed at stopping or reversing the immune system response that causes diabetes: the attack on insulin-secreting cells in the pancreas. This attack must be stopped so that any therapies involving replacing or regenerating insulin-producing cells can work long-term.
Within Immune Therapies, JDRF is prioritizing antigen-specific therapies – which target particular immune cells rather than the entire immune system – because of their potential to produce the safest, most effective treatments.
Specific research goals, funding facts, and more information
Your support of JDRF’s Immune Therapies research will help JDRF accelerate progress toward developing drugs and other therapies to stop and ultimately prevent the immune attack that causes type 1 diabetes.
For more information, or to make directed gift to immune therapies research, contact Jack Hickethier (415) 597-6303.

JDRF’s Complications Therapies research focuses on ways to prevent the devastating long-term complications that can accompany diabetes, including diseases of the eyes, nerves, and kidneys. The aim is to stop complications from starting and from getting worse, with the hope that the body can repair any damage. Eventually, it may be possible to prevent complications from ever taking hold in people with diabetes.
One of the key projects in this area will be to examine the genes and gene modifiers that protect some people from diabetic complications, particularly kidney disease. Through the study of “genetic resistance,” researchers will identify new gene targets and pathways that can then be translated into protective therapies that block complications from developing.
Specific research goals, funding facts, and more information
Your support of JDRF’s Complications Therapies research will help us accelerate progress toward developing drugs and other therapies to stop, reverse, and ultimately prevent the complications of diabetes.
For more information, or to make directed gift to complications therapies research, contact Jack Hickethier (415) 597-6303.

To help you better understand what is involved in participating in a clinical trial, and to simplify the process of finding trials that are of interest to you (or your child), JDRF has created an online customized clinical trials listing service - the JDRF Clinical Trials Connection.

JDRF offers a variety of local and national e-publications to help you stay connected to the information you care about.

As the leading charitable funder of diabetes research worldwide, the Juvenile Diabetes Research Foundation International offers a wide variety of grants and fellowships to qualified diabetes researchers.
Visit the JDRF International website to learn more.
